Concentrated bone marrow aspirate and application for the treatment of osteochondral lesion and outcome

As osteochondral defects heal spontaneously or as a result of marrow stimulation, bone clot develops inside the cartilage defect. In clot-filled defect, MSCs from subchondral move in, develop into chondrocytes and osteoblasts, eventually create repair tissue. It is believed that applying aspirate (BMA) to stimulation will improve since it may serve source growth factors promote both chondrogenesis repair. Furthermore, BMA offers three-dimensional environment help even more while safeguarding structural changes. this treatment, concentrated cells (BMAC), hyaluronic acid, fibrin gel are applied after microfracture. The surgical procedure involved debridement lesion, microfracture, application BMAC with HA gel.